Colts vs. Bills Free Pick and Latest Betting Odds – Week 1

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Gambling911.com has your Colts vs. Bills free pick and latest betting odds for 2015 Week 1.

Week 1 NFL Odds at Diamond Sportsbook

Indianapolis Colts -2.5, total 45.5

Colts Wary of Bills New QB

The Buffalo Bills will have a new starting quarterback this season as Tyrod Taylor takes over. Indianapolis head coach Chuck Pagano said that his team needs to be ready for the speed of Taylor. "Better get a package in to have somebody fast enough so when he takes off." Pagano said, “If you’ve got a guy that’s as athletic and mobile as Tyrod is, then you have to plan accordingly.” Taylor will have a lot of weapons around him although newcomer LeSean McCoy is questionable for this contest. Even without McCoy, the Bills have Percy Harvin, Sammy Watkins and Charles Clay so Taylor will have a lot of options to choose from.

Bills Looking to Run First

With a new starting quarterback and facing a potent offense, the Bills want to run the ball on Sunday. Even if they don’t have McCoy in the backfield they still expect to run it a lot. The Bills added veteran Richie Incognito and rookie John Miller to bolster the offensive line and Buffalo will be facing a Colts defense that has been weak against the run.

Game Notes

The Colts are 5-2-1 ATS in the last 8 meetings. The home team is 7-3-1 ATS in the last 11 meetings. The Colts are 5-1 ATS in their last 6 games in September. The Colts are 19-7-1 ATS in their last 27 vs. the AFC. The Colts are 1-6 ATS in their last 7 games in Week 1. The Bills are 8-2 ATS in their last 10 games in Week 1. The Over is 4-0 in the Colts last 4 games in September. The Under is 4-1 in the Colts last 5 road games. The Under is 5-0 in the Bills last 5 home games. The Under is 13-3 in the Bills last 16 games overall. The Under is 4-1 in the last 5 meetings in Buffalo

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