Panthers vs. 49ers Anytime Touchdown Scorer Prop Bet: Christian McCaffrey, Rico Dowdle, George Kittle

Written by :

C Costigan

Published on :

24 November, 2025

Christian McCaffrey is a big -350 favorite to score an anytime touchdown in Monday night's game between the Panthers and 49ers. San Francisco comes into this one as a -7.5 home favorite.

McCaffrey rushed 13 times for 81 yards and two touchdowns in the 49ers’ Week 11 win over the Cardinals, adding five catches for 40 yards and a touchdown.

From NBC Edge:

McCaffrey kept chugging along as the 49ers’ starting running back and best receiver, scoring a grand total of three touchdowns on the day. His first score was from one yard out after a Skyy Moore 98-yard kick return to open the game. The other pair of scores also came from inside the 10-yard line as the 49ers poured it on against the Cardinals. The 29-year-old is on pace to surpass 400 total touches on the season. No nuance to add here, McCaffrey is a definitive top-three RB play for Week 12 and the rest of the season.

Rico Dowdle was priced at -145 to score a touchdown Monday night.

Dowdle rushed 19 times for 45 yards in the Panthers’ Week 11 win over the Falcons, adding five carries for 55 yards.

George Kittle pays out $125 for every $100 bet should he score a touchdown at any point during this game.

caught all six of his targets for 67 yards and two touchdowns in the 49ers’ Week 11 win over the Cardinals.

Touchdown Prop Bets - Panthers vs. 49ers

Any Time
First
Last
Christian McCaffrey
-350
+240
+400
Rico Dowdle
-145
+550
+550
George Kittle
+125
+650
+1000
Tetairoa McMillan
+150
+1000
+850
Jauan Jennings
+180
+950
+1300
Ricky Pearsall
+210
+1000
+1500
Xavier Legette
+400
+2200
+1600
Jalen Coker
+400
+2200
+1600
Brian Robinson Jr.
+440
+2700
+1900
Brock Purdy
+470
+2500
+2200
Ja'Tavion Sanders
+480
+2700
+1700
Chuba Hubbard
+550
+3000
+2200
Kyle Juszczyk
+650
+7000
+2200
San Francisco Defense
+650
+4000
+2500
Tommy Tremble
+750
+8000
+2200
Bryce Young
+800
+4000
+3300
DeMarcus Robinson
+950
+7500
+4000
Jake Tonges
+1000
+8000
+4000
Kendrick Bourne
+1000
+8000
+4000
Carolina Defense
+1000
+5000
+5000
James Mitchell
+1100
+10000
+3300
Mitchell Evans
+1100
+10000
+3300
Brycen Tremayne
+1100
+10000
+3300
Luke Farrell
+1500
+10000
+5500
Hunter Renfrow
+1700
+10000
+4500
Jimmy Horn Jr.
+1700
+10000
+4500
Skyy Moore
+1800
+10000
+5000
Isaac Guerendo
+2200
+10000
+6000
Trevor Etienne
+3000
+10000
+8000