2025 NFL Week 1 Spreads and Totals Now Available
Published on:
May/14/2025
NFL games have been trickling out since Monday, and now we have the full Week 1 schedule.
The guys at BetOnline.ag are the first to publish spreads for all 16 games of Week 1.
NFL Week 1 Lines
Thursday September 4
- Dallas Cowboys at Philadelphia Eagles (-7, 47)
Friday September 5
- Kansas City Chiefs at Los Angeles Chargers (+2.5, 44)
Note: Technically the Chargers are the home team, but the game is at a neutral site in Brazil.
Sunday September 7
- Miami Dolphins at Indianapolis Colts (-1.5)
- Las Vegas Raiders at New England Patriots (-2.5)
- Pittsburgh Steelers at New York Jets (N/A due to Rodgers/QB situation)
- Cincinnati Bengals at Cleveland Browns (+5)
- Carolina Panthers at Jacksonville Jaguars (-2.5)
- New York Giants at Washington Commanders (-7)
- Tampa Bay Buccaneers at Atlanta Falcons (pick 'em)
- Arizona Cardinals at New Orleans Saints (+2)
- Detroit Lions at Green Bay Packers (pick 'em)
- Tennessee Titans at Denver Broncos (-6.5)
- Houston Texans at Los Angeles Rams (-2.5)
- San Francisco 49ers at Seattle Seahawks (+2.5)
- Baltimore Ravens at Buffalo Bills (-1, 53.5)
Monday September 8
- Minnesota Vikings at Chicago Bears (pick 'em, 44.5)
