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Nyquist had odds of winning a Triple Crown that would pay out $22 for every $10 bet.
On Tuesday, his camp said they were feeling comfortable about his chances following a statement win at Saturday’s Kentucky Derby.
"He's not going to allow another horse to beat him. He always has something left," jockey Mario Gutierrez said of Nyquist. "If someone's coming late, he can win by five lengths or he can win by a nose. If anyone is coming late, I'll know he'll have something else."
Nyquist was 7-for-7 heading into the Derby, making him the first unbeaten winner here since Big Brown in 2008.
Early Odds to Win the 2016 Preakness Stakes (subject to change)
Nyquist 4-5
Exaggerator 9-2
Stradivari 8-1
Gun Runner 10-1
Collected 14-1
Destin 16-1
Mor Spirit 16-1
Creator 16-1
Uncle Lino 16-1
Swipe 16-1
Cherry Wine 20-1
Outwork 20-1
Fellowship 20-1
Dazzling Gem 20-1
Lani 33-1
- Don Shapiro, Gambling911.com
