Indianapolis Colts vs. San Francisco 49ers Pick – Odds and Predictions

Written by:
Mike Taylor
Published on:
Indianapolis Colts vs. San Francisco 49ers Pick – Odds and Predictions has your Indianapolis Colts vs. San Francisco 49ers pick along with the latest odds for this game.

Free Prediction Given by lead handicapper, Mike Taylor

Current line: San Francisco – 10 / Over & Under at 46

Time:  Sunday, September 22, 4:25 pm (EST) CBS, DirectTv, NFL Red Zone

The Indianapolis Colts are going to find themselves in a very interesting position against the San Francisco 49ers. Last week for the 49ers, it was a raucous crowd and a great performance from Seattle that took them off their high horse victory over Green Bay. As we stated before, the Niners quarterback is still young and hasn’t been hit hard. Watch for this, because it’s when he gets a taste of reality that the team starts to loosen up over the field.

The Indiana team is definitely a hard-nosed football squad, and they are starting to come together and look like that team of old. Even without Manning, Luck is on their side, and yes, pun is intended. The team is quite good at keeping plays alive, and that’s where the San Francisco defense can in fact get a slight edge. However, Andrew Luck is an athlete, he’s going to be able to read a great deal of the defense and shrug off a lot of defenders, as he’s done in the past.

The 49ers are good on offense, and they have a lot of power in their running game as well as their mobile quarterback. If they can open up on the option and run, Indianapolis will have a hard time containing the score. Just like the Ravens had a few issues against the Niners during the Superbowl, look for the same kind of problems to develop with the inexperienced ends on the Colts. It will be surprising to see if there aren’t a few plays that get the mobile quarterback running past the ends into the sidelines.

The Match Up:

The San Francisco team is going to be at home, they are going to be healthy, and will be mad about their performance last week in Seattle. So much so that the Indianapolis team will be getting hit hard on all sides of the field, and that may be the one caveat that will get them to fall over. The Colts are a good overall team, but they are going into hostile territory and will most likely go down in a close one. If they can’t contain the passing game, and they allow a lot of yards on the ground, this is going to be a no brainer. The San Francisco 49ers get a – 10 from us on this one, and they’ll definitely prove yet again why they have one of the best squads in the league.

The Edge:

San Francisco – 10 is our pick. Prediction: San Francisco – 10

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