2025 Week 4 Betting Lines

Submitted by C Costigan on

Written by :

C Costigan

Published on :

Three blocked field goal attempts in the final two minutes of three early-afternoon games kicked off a crazy Week 3 in the National Football League.

And then we witnessed a menagerie of blocked kicks throughout the day!

It was an exciting week as many outcomes were decided in the last minute of the game.

What will be in store for Week 4. Below are the 2025 Week 4 NFL opening lines, and if there’s a big movement from the look-ahead numbers, that will be notated.

NFL Week 4 spreads are subject to change.

BetOnline Sportsbook – NCAA Football Welcome Bonus

NFL Week 4 Lines

 

Thursday, September 25, 2025

 

  • Seattle Seahawks at Arizona Cardinals (-1.5)
    • Lookahead line was –2.5

Sunday, September 28, 2025

 

  • Minnesota Vikings (-1.5) at Pittsburgh Steelers
    • Look-ahead line was Steelers -1.

 

  • Washington Commanders (-3) at Atlanta Falcons
    • Look-ahead line was -1.

 

  • New Orleans Saints at Buffalo Bills (-16.5)
    • Look-ahead line was –15.5

 

  • Philadelphia Eagles (-3) at Tampa Bay Buccaneers

 

  • Carolina Panthers at New England Patriots (-4)
    • Look-ahead line was –5.5

 

  • Cleveland Browns at Detroit Lions (-8.5)
    • Look-ahead line was -10.

 

  • Tennessee Titans at Houston Texans (-7)

 

  • Los Angeles Chargers (-6) at New York Giants

 

  • Jacksonville Jaguars at San Francisco 49ers (-3.5)

 

  • Indianapolis Colts at Los Angeles Rams (-4)
    • Look-ahead line was -5.

 

  • Chicago Bears at Las Vegas Raiders (-1.5)
    • Look-ahead line was -2.5.

 

  • Baltimore Ravens (-3) at Kansas City Chiefs

 

  • Green Bay Packers (-6) at Dallas Cowboys
    • Look-ahead line was -5.

Monday, September 29, 2025

 

  • New York Jets at Miami Dolphins (-2.5)

 

  • Cincinnati Bengals at Denver Broncos (-7.5)
    • Look-ahead line was -6.5.

Related Content

Top Gambling News Stories for Wednesday September 23, 2026

Top Gambling News Stories for Wednesday September 23, 2026

Top Trending: ACR Poker - Ceasars Acquisition By Fertitta Gaming - Northwest Indiana Sports Betting Ring - Jimmy the Greek James Gerodemo - Kalshi Margin Trading - Derek Utley - Trump Social Media Firm Co-Founder Casino Embezzlement
How a Casino's Licence Number Predicts Its Payout Reliability in Canada

How a Casino's Licence Number Predicts Its Payout Reliability in Canada

The Canadian market Gambling911.com has watched grow for two decades is now one of the more tightly regulated iGaming environments in North America, and the small print at the bottom of a licensed casino page is doing more work than most players realize.
VegasGems Fish Game Platforms: Fire Kirin, Orion Stars, Ultra Panda & Vegas X Compared

VegasGems Fish Game Platforms: Fire Kirin, Orion Stars, Ultra Panda & Vegas X Compared

Every fish arcade platform offers fish shooting games. As a result, players may assume the experience is similar across the board. However, that is far from the truth, as the best fish game platforms have their own unique features and online fish games to choose from.

 Initiative Highlights Tribal Government Gaming’s $26.5 Billion in Economic Impact Across California

Initiative Highlights Tribal Government Gaming’s $26.5 Billion in Economic Impact Across California

While many Californians are familiar with tribal gaming, far fewer are aware of the industry's broader economic impact, including the jobs it supports, the wages it generates, and the billions of dollars it contributes to communities across the state.