2025 College Football Lines Week 2 Released

Submitted by C Costigan on

Written by :

C Costigan

Published on :

BetOnline has released their 2025 Week 2 college football betting lines following some awesome games in Week 1. 

BetOnline Sportsbook – NCAA Football Welcome Bonus

***Note: FBS vs FCS game lines don’t get posted until later in the week.

Week 2 College Football Lines

Friday, September 5, 2025

  • James Madison at Louisville (-15)
  • Northern Illinois at Maryland (-16½)

Saturday, September 6, 2025

  • San José State at Texas (-36)
  • Florida International at Penn State (-42)
  • Illinois (-2½) at Duke
  • Baylor at SMU (-3)
  • Kennesaw State at Indiana (-35½)
  • Iowa at Iowa State (-3½)
  • Kent State at Texas Tech (-49)
  • Virginia at NC State (-3)
  • Central Michigan at Pittsburgh (-21½)
  • UConn at Syracuse (-7½)
  • Liberty (-6½) at Jacksonville State
  • Utah State at Texas A&M (-29½)
  • Troy at Clemson (-32)
  • Oklahoma State at Oregon (-28)
  • Ole Miss (-9½) at Kentucky
  • Kansas at Missouri (-7)
  • Miami (OH) at Rutgers (-14)
  • Fresno State at Oregon State (-2½)
  • Bowling Green at Cincinnati (-18)
  • Texas State at UTSA (-6)
  • Delaware at Colorado (-23½)
  • UAB at Navy (-21)
  • North Texas at Western Michigan
  • Middle Tennessee at Wisconsin (-28)
  • West Virginia (-3) at Ohio
  • South Florida at Florida (-19)
  • Arkansas State at Arkansas (-21½)
  • Missouri State at Marshall (-10)
  • Army at Kansas State (-15)
  • North Carolina at Charlotte
  • Houston (-13½) at Rice
  • Memphis (-14) at Georgia State
  • Tulane (-10½) at South Alabama
  • Western Kentucky at Toledo (-5½)
  • Louisiana Tech at LSU (-37½)
  • Arizona State (-7) at Mississippi State
  • Michigan at Oklahoma (-4½)
  • Ball State at Auburn (-43½)
  • Vanderbilt at Virginia Tech (currently OTB)
  • Akron at Nebraska (-34)
  • Georgia Southern at USC (-28)
  • Boston College at Michigan State (-3)
  • UL Monroe at Alabama (-37½)
  • UCLA (-2) at UNLV
  • Tulsa (-2½) at New Mexico State
  • San Diego State at Washington State (-3)
  • Stanford at BYU (-18½)
  • Sam Houston at Hawai'i (-9½)

Related Content

2026 NFL Week 4, NCAAF Week 5 Spreads

2026 NFL Week 4, NCAAF Week 5 Spreads

The Packers-Bucs spread is off the board because of Mayfield's uncertain status. The other games OTB are due to the Sunday and Monday night games still to be played.
Bucs Bowles First NFL Head Coach Fired Odds Watch

Bucs Bowles First NFL Head Coach Fired Odds Watch

Dan Quinn, head coach for the Commanders, can certainly breathe a sigh of relief after knocking off the reigning Super Bowl champs this week.
Rams vs. Broncos Total Receiving Yards Prop Bets: Davante Adams, Jaylen Waddle, Terrance Ferguson

Rams vs. Broncos Total Receiving Yards Prop Bets: Davante Adams, Jaylen Waddle, Terrance Ferguson

Devante Adams pays $130 for every $100 bet to have the most receiving yards in this game and an over/under of 71.5.
Rams vs. Broncos Touchdown Scorer Prop Bets: Kyren Williams, Davante Adams, J.K. Dobbins

Rams vs. Broncos Touchdown Scorer Prop Bets: Kyren Williams, Davante Adams, J.K. Dobbins

Gambling911.com has your touchdown scorer prop bets for the Rams vs. Broncos Sunday night game.