Bills vs. Broncos Point Spread – Fantasy Profile for Peyton Manning, Kyle Orton

Submitted by Mary Montgomery on

Written by :

Mary Montgomery

Published on :

The Bills vs. Broncos point spread had Denver as a -10 home favorite.  65% of the action was coming in on Denver here.  Claim Your FREE $250 Here (use bonus code G911).

Buffalo comes into this game with a surprising 7-5 record Straight Up while Denver is 9-3.  Both teams have paid out six times apiece to bettors.

Don’t expect this one to be a cakewalk for Denver.  The Bills have the best defensive efficiency in the NFL (4.5 expected points added per game), along with the most sacks (48) this season.  Buffalo’s defense leads the NFL in sacks (48) while posting the 2nd best opponent Total QBR (39.6). 

Peyton Manning is 7-4 in his career against the Bills. He has just 13 pass TD and 10 interceptions in 11 career games against the Bills.  With the Bills defense now allowing a passing touchdown in four of its past five games, fantasy owners beware when it comes to Manning this week.

The Bills are 10-25-1 Against The Spread in their last 36 games following a Straight Up win, 1-6 ATS in their last 7 road games vs. a team with a winning home record and are 2-10 ATS in their last 12 games after allowing less than 15 points in their previous game.

The Broncos have been red hot during the month of December, going 8-1 Against The Spread.

Denver is giving up the seventh-most fantasy points to opposing quarterbacks this season so we don’t recommend having the Bills starting QB in any fantasy lineup this week.

Fantasy aficionados should also be made aware that the Bills allow the second-fewest fantasy points to opposing running backs.

- Mary Montgomery, Gambling911.com

 

Related Content

NFL Yardage Leaders Odds 2026

NFL Yardage Leaders Odds 2026

It’s a bit surprising to see that there have been 18 different players lead the league in passing, receiving and rushing categories this decade. We thought there would’ve been more repeats.
Rams vs. Chiefs Betting Markets Preseason 2026

Rams vs. Chiefs Betting Markets Preseason 2026

The Chiefs are a -2.5 home favorite here.
Betting Markets: Broncos vs. Falcons, Dolphins vs. Commanders, Bucs vs. Jets Preseason NFL

Betting Markets: Broncos vs. Falcons, Dolphins vs. Commanders, Bucs vs. Jets Preseason NFL

Though betting markets are mostly limited, gamblers were still wagering on this week's NFL preseason games.
Green Bay Packers vs. Pittsburgh Steelers Betting Markets - Preseason NFL August 13

Green Bay Packers vs. Pittsburgh Steelers Betting Markets - Preseason NFL August 13

Thursday evening's preseason NFL game between the Green Bay Packers and Pittsburgh Steelers featured limited betting markets and live in-play wagering here. The spread on this game was Packers -2.5.