2025 College Football Lines Week 2 Released

Submitted by C Costigan on

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C Costigan

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BetOnline has released their 2025 Week 2 college football betting lines following some awesome games in Week 1. 

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***Note: FBS vs FCS game lines don’t get posted until later in the week.

Week 2 College Football Lines

Friday, September 5, 2025

  • James Madison at Louisville (-15)
  • Northern Illinois at Maryland (-16½)

Saturday, September 6, 2025

  • San José State at Texas (-36)
  • Florida International at Penn State (-42)
  • Illinois (-2½) at Duke
  • Baylor at SMU (-3)
  • Kennesaw State at Indiana (-35½)
  • Iowa at Iowa State (-3½)
  • Kent State at Texas Tech (-49)
  • Virginia at NC State (-3)
  • Central Michigan at Pittsburgh (-21½)
  • UConn at Syracuse (-7½)
  • Liberty (-6½) at Jacksonville State
  • Utah State at Texas A&M (-29½)
  • Troy at Clemson (-32)
  • Oklahoma State at Oregon (-28)
  • Ole Miss (-9½) at Kentucky
  • Kansas at Missouri (-7)
  • Miami (OH) at Rutgers (-14)
  • Fresno State at Oregon State (-2½)
  • Bowling Green at Cincinnati (-18)
  • Texas State at UTSA (-6)
  • Delaware at Colorado (-23½)
  • UAB at Navy (-21)
  • North Texas at Western Michigan
  • Middle Tennessee at Wisconsin (-28)
  • West Virginia (-3) at Ohio
  • South Florida at Florida (-19)
  • Arkansas State at Arkansas (-21½)
  • Missouri State at Marshall (-10)
  • Army at Kansas State (-15)
  • North Carolina at Charlotte
  • Houston (-13½) at Rice
  • Memphis (-14) at Georgia State
  • Tulane (-10½) at South Alabama
  • Western Kentucky at Toledo (-5½)
  • Louisiana Tech at LSU (-37½)
  • Arizona State (-7) at Mississippi State
  • Michigan at Oklahoma (-4½)
  • Ball State at Auburn (-43½)
  • Vanderbilt at Virginia Tech (currently OTB)
  • Akron at Nebraska (-34)
  • Georgia Southern at USC (-28)
  • Boston College at Michigan State (-3)
  • UL Monroe at Alabama (-37½)
  • UCLA (-2) at UNLV
  • Tulsa (-2½) at New Mexico State
  • San Diego State at Washington State (-3)
  • Stanford at BYU (-18½)
  • Sam Houston at Hawai'i (-9½)

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