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The USC vs. SMU betting line for this March Madness tournament game had the Mustangs as a big -6.5 favorite.
USC is a number 11 seed with SMU a 6 seed.
Southern California owned a 25-9 record Straight Up and right around the .500 mark Against The Spread. They have covered in half of their last ten games overall.
The Mustangs are 30-4 Straight Up and 22-6-1 ATS. They have covered in 80 percent of their last ten games. In fact, they are 20-5-1 ATS in their last 26 games overall.
- Tyrone Black, Gambling911.com
