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The Notre Dame vs. Louisville betting odds had the Cardinals as a -8 home favorite. LIVE IN-PLAY WAGERING is available for this game.
The Fighting Irish and Cardinals have been red hot both Straight Up and Against The Spread. Their Straight Up records are identical at 23-7 while Notre Dame has an impressive 15-8-1 ATS record and Louisville more so at 17-10-1. Both teams have covered the spread in only half of their last ten games overall.
Notre Dame has won the last three in this series.
The OVER (146.5) is 11-3 in the last 14 meetings.
- Dan Shapiro, Gambling911.com
