Expert Picks on the 49ers vs. Lions Game Week 1

Submitted by Don Shapiro on

Written by :

Don Shapiro

Published on :

Expert Picks on the 49ers vs. Lions Game Week 1

BetUS host Matt Landes is joined by expert sports bettors Las Vegas Cris and Scott Kellen to preview the Week 1 matchup between the San Francisco 49ers and the Detroit Lions.  BetUS offers a generous welcome bonus (max bonus $2500) - Ask about their amazing 200% crypto bonus.

BetUS-Square-Banner-NFL.gif

  • The 49ers are as high as a -9 point favorite at most books.
  • The line has moved from -7.5 to -9 with more than 75% of the public love coming in on San Francisco.
  • San Francisco is the third team in the last 20 seasons to be a road favorite of at least seven points in Week 1 after having a losing record the year previous, with the previous two losing outright.
  • San Francisco has lost its last five games outright as a favorite.
  • Kyle Shanahan is 1-7-1 ATS (5-4 outright) as a favorite of at least seven points.
  • Detroit games have gone over the total in each of the last 10 Week 1 games.
  • BetUS resident Lions fan Las Vegas Cris: "It's how these teams stack up.  San Francisco is a much better team when they are healthy and the Lions are a mess replacing 11,000 snaps from last year with new talent or lack thereof."

- Don Shapiro, Gambling911.com

Related Content

Live Gambling News, Top Trending: Updates 24/7 - Sunday June 21 2026

Live Gambling News, Top Trending: Updates 24/7 - Sunday June 21 2026

FIFA World Cup - Halle Final - Taylor Fritz vs. Frances Tiafoe - Michigan Men Charged in Vegas Kidnapping - Oneida Casino Shooting - Seminole Hard Rock Hotel & Casino Hollywood Gazebo Collapse - Iran Conflict
PPH World Cup Game Prop Bets - Argentina vs. Austria

PPH World Cup Game Prop Bets - Argentina vs. Austria

Argentina is a -200 favorite while Austria promises a payout of US$600 for every US$100 bet to have the upset.
New Jersey Councilman Who Previously Admitted to Several Murders as Mob Enforcer Arrested for Extortion

New Jersey Councilman Who Previously Admitted to Several Murders as Mob Enforcer Arrested for Extortion

John Alite once claimed to have committed 15 murders, shot 30 to 40 people and beaten more than one hundred others with pipes and baseball bats.
First, Anytime Goal Scorer Prop Bet Payout Odds - New Zealand v Egypt: Mohamed Salah, Omar Marmoush, Mostafa Zico

First, Anytime Goal Scorer Prop Bet Payout Odds - New Zealand v Egypt: Mohamed Salah, Omar Marmoush, Mostafa Zico

Goalscorer prop bets are available for Mohamed Salah, Omar Marmoush, Mostafa Zico, all courtesy of our friends at BetUS.