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Colts vs. 49ers Expert Predictions - Sunday Night Football

Written by:
Don Shapiro
Published on:
Oct/24/2021

Colts and 49ers meet on Sunday, October 24th. The Colts get back one of their best offensive linemen back while Kyle Shanahan had an extra week to prepare for this game.  The line on this game was coming in at San Francisco -4.

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After a slow start to the season, which included a banged-up Carson Wentz, the Colts seem to have found their stride. Now they get another primetime game against a 49ers team that continues to suffer from injuriesl. Despite that, Shanahan did get extra time to prepare for this game so don’t be surprised if the 49ers pull off the victory at home without key players.

Catch up with BetUS’s host, Matt Landes, who’ll be joined by experts, Las Vegas Cris and Scott Kellen to preview this Colts vs 49ers Sunday Night Football matchup and hook you up with their SNF picks and best bets for this game.

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