2026 NFL Week 4, NCAAF Week 5 Spreads

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2026 NFL Week 4, NCAAF Week 5 Spreads

Quarterback injuries are piling up across the league, and Baker Mayfield is the latest to be maimed.

The Packers-Bucs spread is off the board because of Mayfield's uncertain status. The other games OTB are due to the Sunday and Monday night games still to be played.  Scroll down for all the other lines and place your bets here. 

NFL Week 4 Lines 

Thursday, October 1

  • Pittsburgh Steelers at Cleveland Browns (+2.5)
  • Lookahead line was Browns +1.5

Sunday, October 4

  • Indianapolis Colts vs Washington Commanders (+2)
  • Lookahead line was Commanders +4.
  • Note: Game is in London.
  • New England Patriots at Buffalo Bills (-7)
  • Lookahead line was Bills -5.5
  • New York Jets at Chicago Bears (+3.5)
  • Lookahead line was Bears -3.5.
  • Jacksonville Jaguars at Cincinnati Bengals (-2)
  • Lookahead line was Bengals -2.5
  • Arizona Cardinals at New York Giants (-1.5)
  • Lookahead line was Giants -2.5
  • Los Angeles Rams at Philadelphia Eagles (OTB)
  • Lookahead line was Eagles +2.5.
  • Green Bay Packers at Tampa Bay Buccaneers (OTB)
  • Lookahead line was Bucs +1.5.
  • Tennessee Titans at Baltimore Ravens (-11.5)
  • Lookahead line was Ravens -10.5
  • Dallas Cowboys at Houston Texans (-1.5)
  • Lookahead line was Texans -3
  • Miami Dolphins at Minnesota Vikings (-10.5)
  • Lookahead line was Vikings -10.
  • Kansas City Chiefs at Las Vegas Raiders (+4.5)
  • Lookahead line was Raiders +5.5
  • Denver Broncos at San Francisco 49ers (OTB)
  • Lookahead line was 49ers -3.5
  • Los Angeles Chargers at Seattle Seahawks (-6.5)
  • Lookahead line was Seahawks -6.5
  • Detroit Lions at Carolina Panthers (+2.5)
  • Lookahead line was Panthers +2.5

Monday, October 5

  • Atlanta Falcons at New Orleans Saints (-2.5)
  • Lookahead line was Saints -3.5

 

Week 5 of the college football season has three games involving Top 25 matchups: 

  • Ohio State @ Iowa
  • Alabama @ Mississippi State
  • Florida @ Missouri 

  

Week 5 Football Lines 

Thursday, October 1 

  • Western Kentucky at New Mexico State (-1)
  • North Texas at Tulsa (-2.5) 

Friday, October 2 

  • Pittsburgh at Virginia Tech (-4.5)
  • Liberty at Delaware (+7)
  • Penn State at Northwestern (+3) 

Saturday, October 3 

  • Vanderbilt at Georgia (-24.5)
  • Notre Dame at North Carolina (+21.5)
  • Miami at Clemson (+17)
  • Alabama at Mississippi State (+6)
  • Michigan at Minnesota (+6.5)
  • Boston College at SMU (-20.5)
  • UCF at Houston (-11)
  • Middle Tennessee at Kansas (-19.5)
  • West Virginia at Iowa State (-2)
  • Stanford at Wake Forest (-13)
  • Syracuse at UConn (+5.5)
  • Navy at Air Force (-2.5)
  • Michigan State at Wisconsin (-10)
  • Western Michigan at Buffalo (+15.5)
  • Toledo at Ball State (+18.5)
  • Ohio State at Iowa (+14)
  • Auburn at Tennessee (-7.5)
  • Louisville at NC State (+6)
  • Florida at Missouri (+4)
  • California at UNLV (-2)
  • Virginia at Florida State (+2.5)
  • Memphis at Charlotte (+21.5)
  • Wyoming at North Dakota State (-20)
  • Akron at Central Michigan (-6.5)
  • Eastern Michigan at Massachusetts (-5.5)
  • Ohio at Kent State (+5.5)
  • Bowling Green at Miami (OH) (-14.5)
  • Old Dominion at Georgia State (+1.5)
  • Marshall at James Madison (-16.5)
  • Maryland at Nebraska (-13.5)
  • UTEP at New Mexico (-21.5)
  • Kentucky at South Carolina (-3.5)
  • Purdue at Illinois (-10)
  • Oregon State at Colorado State (+4.5)
  • BYU at TCU (+6.5)
  • Arkansas at Texas A&M (-14)
  • UTSA at Rice (+10.5)
  • Georgia Southern at Coastal Carolina (PK)
  • UL Monroe at South Alabama (-14)
  • Texas Tech at Colorado (+14.5)
  • Washington at USC (-9)
  • Utah State at Boise State (-21)
  • Temple at South Florida (-5.5)
  • Army at Louisiana Tech (+3.5)
  • Indiana at Rutgers (+23.5)
  • Arkansas State at Louisiana (-6)
  • Fresno State at Washington State (+1)
  • Baylor at Arizona State (-3.5)
  • Texas State at San Diego State (+4)
  • Cincinnati at Arizona (-7.5)
  • San José State at Hawai'i (-3) 

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