Bills vs. Panthers Anytime, First Touchdown Scorer Prop Bet: James Cook, Rico Dowdle

Written by :

C Costigan

Published on :

24 October, 2025

Anytime and first touchdown prop bets for Sunday's Bills vs. Panthers game are available at BetUS.

James Cook rushed 17 times for 87 yards in the Bills’ Week 6 loss to the Falcons.

He is priced at -150 to score a touchdown in this game.

From NBC Edge:

He gained more yards on the team’s first possession of the second half than he did the rest of the game, which highlights the general inability of the Buffalo offense to move the football consistently amidst mounting injuries. Losing field stretcher Joshua Palmer early in the second quarter left the offense in a state of one-dimensionality they were unable to overcome in the face of consistent pressure from an aggressive Atlanta defensive front. Cook’s splits in wins versus losses this season are stark, something fantasy managers hope alter course when the Bills exit their Week 8 bye.

Rico Dowdle pays $155 for every $100 bet to score a touchdown here.

Dowdle had 17 rushes for 79 yards in the Panthers’ Week 7 win against the Jets, adding one catch for 17 yards.

Touchdown Prop Bets Bills vs. Panthers

Any Time
First
Last
James Cook
-150
+410
+650
Josh Allen
+105
+650
+700
Rico Dowdle
+155
+950
+900
Tetairoa McMillan
+185
+1200
+900
Khalil Shakir
+210
+1000
+1300
Keon Coleman
+220
+1100
+1400
Chuba Hubbard
+220
+1200
+1100
Dalton Kincaid
+230
+1100
+1500
Xavier Legette
+330
+2000
+1400
Dawson Knox
+370
+2000
+1700
Jalen Coker
+500
+2700
+2000
Buffalo Defense
+550
+3000
+2200
Tommy Tremble
+650
+4000
+2200
Curtis Samuel
+650
+3500
+2700
Ja'Tavion Sanders
+650
+3300
+2500
Ty Johnson
+650
+4500
+1800
Tyrell Shavers
+750
+3500
+3300
Jackson Hawes
+800
+3500
+3500
Mitchell Evans
+800
+5500
+2700
Carolina Defense
+850
+4000
+4000
Ray Davis
+1100
+10000
+2500
Jimmy Horn Jr.
+1100
+6000
+3500
Elijah Moore
+1100
+5500
+5000
Hunter Renfrow
+1100
+6000
+3500
Brycen Tremayne
+1500
+8000
+4500
Trevor Etienne
+2200
+10000
+7000

- Dan Shapiro, Gambling911.com

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