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The Duke Blue Devils vs. Syracuse Orange betting odds had the Orange as a +3.5 home favorite.
Duke is 22-5 Straight Up but just 11-15 Against The Spread playing in front of one of the most devoted College Basketball fan bases in the country.
Syracuse has a less intimidating 16-12 record and is right around the .500 mark Against The Spread.
Though the Orange have failed to cover the spread in their last three games, they had done so in five straight before this recent drought.
Syracuse did win by two points in the last meeting versus Duke. The Orange lost their last home game to Duke in 2015 by eight points.
Syracuse is 7-1 ATS in their last 8 home games.
- Don Shapiro, Gambling911.com
